factor b-in-2 — TargetMol Chemicals

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Search Results for " factor b-in-2 "

Compounds

Cat No.	Product Name	Synonyms	Targets
T62292	Factor B-IN-2
	Factor B-IN-2 is a potent inhibitor (IC50: 1.5 μM) of complement factor B. Factor B-IN-2 can be used to study inflammatory and immune-related diseases.
TWS1977	Kamebakaurin	Kamebakaurine	NF-κB
	1. Kamebakaurin (Kamebakaurine) has the ability to protect the liver from APAP-induced hepatotoxicity, presumably by both inhibiting the inflammatory response and oxidative stress. 2. Kamebakaurin inhibits the expression...		NF-κB
T6S1256	Ruscogenin		NOS , NF-κB , NOD-like Receptor (NLR)
	1. Ruscogenin has anti-inflammatory activity, suppressed zymosan A-evoked peritoneal total leukocyte migration in mice in a dose-dependent manner, 2. Ruscogenin inhibited adhesion of leukocytes to a human umbilical vein ...		NOS , NF-κB , NOD-like Receptor (NLR)
T0798	Triamcinolone	Fluoxyprednisolone,Aristocort,Rodinolone	Glucocorticoid Receptor , COX
	Triamcinolone (Aristocort) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. Upon cell entry, triamcinolone binds to and activates the glucocorticoid receptor, which leads to transloca...		Glucocorticoid Receptor , COX
T1331	Riboflavin phosphate sodium	Riboflavin 5'-phosphate sodium,Vitamin B2 Phosphate Sodium Salt,Flavin mononucleotide,FMN,FMN-Na,riboflavin-5'-phosphate	Endogenous Metabolite
	Riboflavin phosphate sodium (FMN) is the phosphate sodium salt form of riboflavin, a water-soluble and essential micronutrient that is the principal growth-promoting factor in naturally occurring vitamin B complexes. Rib...		Endogenous Metabolite
T27033	CKD-712	CKD 712,CKD712
	CKD-712 is a nuclear factor NF-kappa B inhibitor. CKD-712 suppressed MMP-9, but not MMP-2 and other NF-κB-regulated proteins involved in cancer metastasis such as VEGF. CKD-712 induced cell cycle arrest at G2M phase by s...
T68755	NZ-28
	NZ28, also known as NSC134754, is potent HSF1 inhibitor, which induced inhibition of HSF1, SP1 and NF-κB triggers the loss of the natural killer cell-activating ligands MICA/B on human tumor cells. Heat-shock transcript...
T76277	Vosoritide
	Vosoritide (BMN 111), a modified recombinant C-type natriuretic peptide (CNP) analogue, engages with natriuretic peptide receptor type B (NPR-B) to diminish the function of fibroblast growth factor receptor 3 (FGFR3). Th...
T74683	IONIS-FB-LRx
	IONIS-FB-LRx, a targeted antisense oligonucleotide (ASO) specifically designed to inhibit complement factor B (CFB), effectively lowers circulating CFB levels. This compound has potential applications in geographic atrop...
T76814	Lampalizumab
	Lampalizumab (RG 7417), a humanized monoclonal antibody, selectively inhibits complement Factor D in the alternative complement pathway by binding to an exosite and sterically hindering Factor B's access to the active si...
T83843	2'(3')-O-Anthraniloylguanosine-5'-O-triphosphate sodium	2'(3')-ANT-GTP
	2'(3')-O-Anthraniloylguanosine-5'-O-triphosphate (2'-ANT-GTP) and 3'-ANT-GTP are fluorescent derivatives of GTP that exhibit spontaneous isomerization. 2'(3')-ANT-GTP features an emission peak at 428 nm when excited at 3...
T36608	(±)8-HEPE
	(±)8-HEPE is produced by non-enzymatic oxidation of EPA. It contains equal amounts of 8(S)-HEPE and 8(R)-HEPE. The ability of (±)8-HEPE to induce hatching of E. modestus and B. balanoides eggs is probably due to the pres...